Product Overview
Description:
AdipoUpX™ Human TRPC5 MSCV Particle (Overexpression) is a retroviral vector engineered for stable overexpression of the human TRPC5 gene. TRPC5 is a calcium channel involved in neuronal and metabolic signaling pathways that may influence energy balance. The MSCV system ensures sustained expression in hematopoietic stem cells, stem cells, and mammalian systems. Comprehensive QC ensures safety and reproducibility.
Production Cell Line:
HEK293T
Promoter:
Ubi; CMV; EF1a; Others
Product Availability:
Produced Upon Order
Specification
Titer Test:
qPCR
Insert Verification:
Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.
Sterility Test:
No microbial contamination was detected in any product.
Mycoplasma Test:
No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.
Other QC:
Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.
Storage:
The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.
Stability:
Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.
Shipping Condition:
Our MSCV retroviral products are shipped using dry ice.
Handling Notes:
Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.
Intended Use:
This product is intended for research use only and is not for use in diagnosis or therapeutic applications.
Product Disclaimer:
Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.
Target Profile
Gene Name:
TRPC5
Full Name:
Transient receptor potential cation channel subfamily C member 5
Gene Symbol:
TRP5; PPP1R159
Summary:
TRPC5 encodes a member of the transient receptor potential canonical (TRPC) channel family. It forms multi-pass membrane channels that allow calcium entry in response to receptor stimulation. TRPC5 can function as a homomeric channel or assemble with other TRPC subunits such as TRPC1, TRPC3, and TRPC4. Its activity is regulated through interactions with several signaling and scaffold proteins, including calmodulin and NHERF. Through its role in calcium influx, TRPC5 participates in diverse cellular signaling pathways.
