AdipoUpX™ Human PLIN1 MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human PLIN1 MSCV Particle (Overexpression) is a high-titer MSCV particle designed for the specific and efficient stable expression of the human PLIN1 gene. Perilipin-1 is essential for the stabilization of lipid droplets and the regulation of lipolysis in adipocytes. This stable integration system is optimized for stem cells, hematopoietic stem cells, etc., making it an ideal tool for investigating lipid droplet dynamics. The product supports flexible reporter gene customization and is verified through comprehensive quality control screening to ensure experimental safety.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: PLIN1

Full Name: Perilipin 1

Gene Symbol: PERI; PLIN; FPLD4

Gene ID: 5346

RefSeq ID-1: NP_001138783.1

RefSeq ID-2: NM_001145311.2

Summary: PLIN1 encodes perilipin 1, a protein that coats lipid droplets in adipocytes and regulates their breakdown by hormone-sensitive lipase. When unphosphorylated, it inhibits lipolysis, whereas phosphorylation by cAMP-dependent protein kinase promotes triglyceride mobilization. Variants or dysregulation of PLIN1 affect fat storage and release, influencing obesity risk.

AdipoUpX™ Human PLIN1 MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

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