Product Overview
Description:
AdipoUpX™ Human ANGPTL6 MSCV Particle (Overexpression) provides stable overexpression of the human ANGPTL6 gene, a secreted factor involved in energy expenditure and metabolic regulation. ANGPTL6 has been reported to counteract obesity and improve metabolic balance. The MSCV retroviral platform supports sustained gene expression across stem cells and mammalian systems. Viral quality is confirmed through extensive QC screening.
Production Cell Line:
HEK293T
Promoter:
Ubi; CMV; EF1a; Others
Product Availability:
Produced Upon Order
Specification
Titer Test:
qPCR
Insert Verification:
Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.
Sterility Test:
No microbial contamination was detected in any product.
Mycoplasma Test:
No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.
Other QC:
Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.
Storage:
The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.
Stability:
Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.
Shipping Condition:
Our MSCV retroviral products are shipped using dry ice.
Handling Notes:
Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.
Intended Use:
This product is intended for research use only and is not for use in diagnosis or therapeutic applications.
Product Disclaimer:
Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.
Target Profile
Gene Name:
ANGPTL6
Full Name:
Angiopoietin like 6
Gene Symbol:
AGF; ARP5
Summary:
ANGPTL6 encodes a secreted angiopoietin-like protein involved in angiogenesis, cell differentiation, and metabolic regulation. Circulating ANGPTL6 levels have been proposed as biomarkers for metabolic disorders, including gestational diabetes, and the protein has been implicated in energy balance and lipid metabolism.
