Product Overview
Description:
AdipoUpX™ Human UCP3 MSCV Particle (Overexpression) is a powerful gene delivery tool designed for the stable overexpression of the human UCP3 gene. The UCP3 protein is a key target in the study of mitochondrial uncoupling and thermogenesis. Its structure is optimized for hematopoietic cells, stem cells, etc., providing stable gene integration. This product accelerates progress in metabolic research by enabling rapid validation of UCP3's effects on energy expenditure and mitochondrial protection. All products undergo rigorous testing to ensure quality and efficacy.
Production Cell Line:
HEK293T
Promoter:
Ubi; CMV; EF1a; Others
Product Availability:
Produced Upon Order
Specification
Titer Test:
qPCR
Insert Verification:
Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.
Sterility Test:
No microbial contamination was detected in any product.
Mycoplasma Test:
No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.
Other QC:
Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.
Storage:
The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.
Stability:
Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.
Shipping Condition:
Our MSCV retroviral products are shipped using dry ice.
Handling Notes:
Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.
Intended Use:
This product is intended for research use only and is not for use in diagnosis or therapeutic applications.
Product Disclaimer:
Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.
Target Profile
Gene Name:
UCP3
Full Name:
Uncoupling protein 3
Gene Symbol:
SLC25A9
Summary:
UCP3 is a mitochondrial inner membrane protein whose primary role is to act as a safety exhaust valve for the proton gradient. By facilitating a controlled "proton leak," UCP3 uncouples respiration from ATP production, converting stored energy into non-shivering heat (thermogenesis). While predominantly found in skeletal muscle, its function is protective: it helps mitigate oxidative stress by exporting excess fatty acids from the mitochondria, especially during periods of high lipid supply. UCP3 is a key molecular candidate for developing treatments aimed at increasing energy expenditure and reducing fat accumulation.
