AdipoUpX™ Human SERPINA12 MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human SERPINA12 MSCV Particle (Overexpression) is a specialized retroviral vector designed to drive the stable expression of vaspin (visceral adipose tissue-derived serine protease inhibitor). This adipokine is known for its insulin-sensitizing and anti-inflammatory effects in metabolic disorders. Its structure is optimized for high-fidelity integration in stem cells, hematopoietic stem cells, and diverse mammalian cell lines. Each product undergoes rigorous quality control, including titer, sterility, and mycoplasma testing, to ensure that research into adipokine signaling is supported by a safe system.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: SERPINA12

Full Name: Serpin family A member 12

Gene Symbol: OL-64

Gene ID: 145264

RefSeq ID-1: NP_001291390.1

RefSeq ID-2: NM_001304461.2

Summary: SERPINA12, or Vaspin, is an adipokine that functions as a molecular inhibitor of enzymes involved in glucose production. It acts as an insulin-sensitizing factor that improves glucose tolerance and regulates lipid metabolic processes. Its levels often rise as a compensatory mechanism in response to obesity and high-fat diets.

AdipoUpX™ Human SERPINA12 MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

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