Product Overview
Description:
AdipoUpX™ Human TBC1D1 MSCV Particle (Overexpression) is a professionally engineered retroviral particle designed for stable overexpression of the human TBC1D1 gene. TBC1D1 is involved in glucose transporter regulation and skeletal muscle energy metabolism, with strong relevance to insulin sensitivity and obesity. The MSCV system provides efficient genomic integration in hematopoietic stem cells, stem cells, and mammalian cell models for metabolic pathway studies. All products undergo rigorous quality control to ensure reproducibility and safety.
Production Cell Line:
HEK293T
Promoter:
Ubi; CMV; EF1a; Others
Product Availability:
Produced Upon Order
Specification
Titer Test:
qPCR
Insert Verification:
Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.
Sterility Test:
No microbial contamination was detected in any product.
Mycoplasma Test:
No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.
Other QC:
Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.
Storage:
The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.
Stability:
Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.
Shipping Condition:
Our MSCV retroviral products are shipped using dry ice.
Handling Notes:
Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.
Intended Use:
This product is intended for research use only and is not for use in diagnosis or therapeutic applications.
Product Disclaimer:
Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.
Target Profile
Gene Name:
TBC1D1
Full Name:
TBC1 domain family member 1
Gene Symbol:
TBC; TBC1
Summary:
TBC1D1 encodes a member of the TBC-domain–containing protein family, characterized by a conserved region of approximately 180–200 amino acids. It shares homology with several proteins involved in vesicular trafficking and cellular regulation, including yeast Bub2 and CDC16. TBC1D1 is implicated in pathways governing cellular growth and differentiation.
