Product Overview
Description:
AdipoUpX™ Human PPARA MSCV Particle (Overexpression) is a high-titer MSCV particle designed for the specific and efficient stable expression of the human PPARA gene. PPAR-alpha is a master regulator of fatty acid oxidation and ketogenesis. This stable integration system is optimized for stem cells, hematopoietic stem cells, etc., making it a perfect tool for studying lipid metabolism and energy homeostasis in permanent cell models. Comprehensive quality control, including titer and mycoplasma testing, ensures the performance and safety of every batch.
Production Cell Line:
HEK293T
Promoter:
Ubi; CMV; EF1a; Others
Product Availability:
Produced Upon Order
Specification
Titer Test:
qPCR
Insert Verification:
Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.
Sterility Test:
No microbial contamination was detected in any product.
Mycoplasma Test:
No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.
Other QC:
Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.
Storage:
The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.
Stability:
Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.
Shipping Condition:
Our MSCV retroviral products are shipped using dry ice.
Handling Notes:
Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.
Intended Use:
This product is intended for research use only and is not for use in diagnosis or therapeutic applications.
Product Disclaimer:
Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.
Target Profile
Gene Name:
PPARA
Full Name:
Peroxisome proliferator activated receptor alpha
Gene Symbol:
PPAR; NR1C1; hPPAR; PPARalpha; PPAR-alpha
Summary:
PPARA encodes peroxisome proliferator-activated receptor alpha, a nuclear transcription factor that regulates genes involved in lipid metabolism, cell proliferation, and inflammation. PPARα is activated by compounds such as hypolipidemic drugs, herbicides, and leukotriene antagonists. Multiple transcript variants have been identified, with two full-length isoforms characterized to date.
