AdipoUpX™ Human FAS MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human FAS MSCV Particle (Overexpression) enables stable overexpression of the human FAS gene, encoding fatty acid synthase, a central enzyme in lipogenesis. Dysregulated FAS activity contributes to excessive lipid accumulation in obesity. The MSCV system ensures durable gene expression in stem cells and other mammalian cell lines used in metabolic research. Viral preparations undergo validated QC procedures to ensure experimental reliability.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: FAS

Full Name: Fas cell surface death receptor

Gene Symbol: APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6

Gene ID: 355

RefSeq ID-1: NP_000034.1

RefSeq ID-2: NM_000043.6

Summary: FAS encodes a death receptor of the TNF receptor superfamily that initiates programmed cell death through caspase activation. In addition to apoptosis, FAS signaling can activate NF-κB and MAPK pathways, influencing cell proliferation and inflammatory responses. In adipose tissue, altered FAS signaling has been implicated in adipocyte turnover, immune cell activation, and obesity-associated inflammation.

AdipoUpX™ Human FAS MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

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