AdipoUpX™ Human ACSL1 MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human ACSL1 MSCV Particle (Overexpression) is designed for stable delivery of the human ACSL1 gene, which encodes an acyl-CoA synthetase essential for fatty acid activation and lipid metabolism. ACSL1 plays a critical role in adipose tissue function and energy utilization in obesity. The MSCV system supports long-term expression in stem cells, hematopoietic stem cells, and other mammalian cell lines. Each batch undergoes rigorous quality control to ensure consistency and biosafety.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: ACSL1

Full Name: Acyl-CoA synthetase long chain family member 1

Gene Symbol: ACS1; LACS; FACL1; FACL2; LACS1; LACS2

Gene ID: 2180

RefSeq ID-1: NP_001273637.1

RefSeq ID-2: NM_001286708.2

Summary: ACSL1 encodes a long-chain acyl-CoA synthetase that catalyzes the activation of free long-chain fatty acids into fatty acyl-CoA esters. This conversion is essential for directing fatty acids toward β-oxidation, lipid synthesis, or storage. ACSL1 plays a pivotal role in controlling lipid partitioning in metabolic tissues, linking its activity to adiposity, insulin sensitivity, and obesity-related metabolic remodeling.

AdipoUpX™ Human ACSL1 MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

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