AdipoUpX™ Human LPIN2 MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human LPIN2 MSCV Particle (Overexpression) is designed for efficient stable overexpression of the human LPIN2 gene, which encodes a phosphatidate phosphatase involved in lipid metabolism. LPIN2 contributes to triglyceride synthesis and inflammatory regulation, linking it to obesity-related metabolic pathways. The MSCV vector ensures stable expression in stem cells, hematopoietic stem cells, and other mammalian cell lines. Rigorous QC testing, including viral titer, sterility, and mycoplasma screening, is applied.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: LPIN2

Full Name: Lipin 2

Gene Symbol: MJDS; CRMO1

Gene ID: 9663

RefSeq ID-1: NP_001362737.1

RefSeq ID-2: NM_001375808.2

Summary: LPIN2 is a member of the lipin family and is thought to play a major role in human triglyceride metabolism and adipose tissue development. It is considered a candidate gene for lipodystrophy, a condition where the body cannot properly store fat, leading to fatty liver, high triglycerides, and severe insulin resistance. Its function is crucial for healthy fat distribution.

AdipoUpX™ Human LPIN2 MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

Related Products