AdipoUpX™ Human LPL MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human LPL MSCV Particle (Overexpression) is a stable integration tool for the specific and efficient overexpression of the human LPL gene. Lipoprotein lipase is the primary enzyme for triglyceride hydrolysis and fatty acid uptake. By utilizing a vector optimized for hematopoietic stem cells, stem cells, embryonic lineages, etc., this product ensures stable, high-level expression for studying lipid flux. Product quality is guaranteed by rigorous purification and comprehensive QC screening, including titer, sterility, and mycoplasma testing.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: LPL

Full Name: Lipoprotein lipase

Gene Symbol: LIPD; HDLCQ11

Gene ID: 4023

RefSeq ID-1: NP_000228.1

RefSeq ID-2: NM_000237.3

Summary: LPL encodes lipoprotein lipase, a key enzyme expressed in the heart, muscle, and adipose tissue. Functioning as a homodimer, it hydrolyzes triglycerides and serves as a bridging factor for receptor-mediated lipoprotein uptake. Severe mutations causing LPL deficiency lead to type I hyperlipoproteinemia, while milder variants contribute to broader disorders of lipoprotein metabolism, linking LPL to lipid regulation and metabolic homeostasis.

AdipoUpX™ Human LPL MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

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