AdipoUpX™ Human ADIPOQ MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human ADIPOQ MSCV Particle (Overexpression) is a high-titer MSCV particle designed for the specific and efficient stable expression of the human ADIPOQ gene. The vector structure has been optimized for hematopoietic and stem cells, etc. ADIPOQ generates adiponectin, which is crucial for insulin sensitization and metabolic protection. This stable integration system is an ideal tool for investigating the systemic role of adipokines in cellular models. Researchers can study its anti-inflammatory effects and role in metabolic pathways.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: ADIPOQ

Full Name: Adiponectin, C1Q and collagen domain containing

Gene Symbol: ACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1

Gene ID: 9370

RefSeq ID: NM_001177800.2, NP_001171271.1

Summary: ADIPOQ is unique as a gene expressed exclusively by adipose tissue, where it codes for the hormone Adiponectin. This protein circulates widely and acts as an anti-inflammatory, insulin-sensitizing adipokine. Adiponectin is a protective factor whose plasma levels are typically reduced in obese and diabetic patients. Its primary therapeutic interest lies in its ability to enhance insulin signaling and stimulate fatty acid oxidation in muscle and liver, making it a critical biomarker and target for treatments aimed at improving metabolic health and reversing insulin resistance.

AdipoUpX™ Human ADIPOQ MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

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