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Vps34-IN-1
Cat. No.:
OB0225LY-0322
Appearance:
Solid
Purity:
≥97%
Identity:
Confirmed by NMR and LC-MS.
Size:
Add to basket
Product Overview
Description:
Vps34-IN-1 is a specific inhibitor that targets the Vps34 enzyme and plays a role in regulating autophagy and membrane trafficking.
Synonym:
1383716-33-3; 1-((2-((2-Chloropyridin-4-yl)amino)-4'-(cyclopropylmethyl)-[4,5'-bipyrimidin]-2'-yl)amino)-2-methylpropan-2-ol; 1-[[5-[2-[(2-Chloropyridin-4-yl)amino]pyrimidin-4-yl]-4-(cyclopropylmethyl)pyrimidin-2-yl]amino]-2-methylpropan-2-ol; 1-(2-(2-Chloropyridin-4-ylamino)-4'-(cyclopropylmethyl)-4,5'-bipyrimidin-2'-ylamino)-2-methylpropan-2-ol
CAS No.:
1383716-33-3
Compound CID:
57404276
Formula:
C21H24ClN7
Formula Weight:
425.91
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Vps34-IN-1 can be used for autophagy research or play an important role in neurodegenerative disease research.
Library Information
Targets:
PI3K
Receptors:
Vps34
Pathways:
Autophagy; PI3K/Akt/mTOR signaling
Plate Number:
AOCL-5
Plate Location:
b6
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
79 mg/mL; 185.5 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
79 mg/mL; 185.5 mM
ALogP:
3.672
HBA_Count:
5
HBD_Count:
2
Rotatable Bond:
8
