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Vitamin B12 test kit

Ralimetinib dimesylate

Cat. No.: OB0125LY-095
Appearance: Solid
Purity: 99.3%
Identity: Confirmed by NMR and HPLC.
Size:
Ralimetinib dimesylate
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Product Overview

Description: Ralimetinib dimesylate is a small molecule compound that belongs to the MAPK inhibitor and works mainly by inhibiting specific signaling pathways.
Synonym: 862507-23-1; Ralimetinib Mesylate; 5-(2-(Tert-butyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)-3-neopentyl-3H-imidazo[4,5-b]pyridin-2-amine dimethanesulfonate; 5-(2-(Tert-Butyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)-3-(2,2-dimethylpropyl)-3H-imidazo[4,5-b]pyridin-2-amine dimethanesulfonate; 5-[2-Tert-butyl-5-(4-fluoro-phenyl)-1H-imidazol-4-yl]-3-(2,2-dimethyl-propyl)-3H-imidazo[4,5-b]pyridin-2-ylamine dimethanesulfonate; 5-(2-(Tert-butyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)-3-(2,2-dimethylpropyl)-3H-imidazo (4,5-b)pyridin-2-amine methanesulfonate; 5-(2-Tert-butyl-4-(4-fluorophenyl)-1H-imidazol-5-yl)-3-neopentyl-3H-imidazo[4,5-b]pyridin-2-amine dimethanesulfonate
CAS No.: 862507-23-1
Compound CID: 11570805
Formula: C24H29FN6·2CH4O3S
Formula Weight: 612.74

Specification

Targets & IC50: p38α: 7 nM
Stability: 3 years in powder form.
Storage: Storage at -20°C.
Applications: Ralimetinib dimesylate has strong anti-tumor activity and can be used in studies of non-small cell lung cancer and other solid tumor diseases.

Library Information

Targets: Autophagy; p38 MAPK; Apoptosis
Receptors: Apoptosis; Autophagy; p38 MAPK; p38α
Pathways: Autophagy; Apoptosis; MAPK
Plate Number: AOCL-5
Plate Location: b2
Empty Location: a1-h1; a12-h12
Container: 96-well plate
Formulation: 10 mM DMSO
DMSO Max Solubility: 27.5 mg/mL; 44.88 mM
ALogP: 5.117
HBA_Count: 3
HBD_Count: 2
Rotatable Bond: 5
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