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Ralimetinib dimesylate
Cat. No.:
OB0125LY-095
Appearance:
Solid
Purity:
99.3%
Identity:
Confirmed by NMR and HPLC.
Size:
Add to basket
Product Overview
Description:
Ralimetinib dimesylate is a small molecule compound that belongs to the MAPK inhibitor and works mainly by inhibiting specific signaling pathways.
Synonym:
862507-23-1; Ralimetinib Mesylate; 5-(2-(Tert-butyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)-3-neopentyl-3H-imidazo[4,5-b]pyridin-2-amine dimethanesulfonate; 5-(2-(Tert-Butyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)-3-(2,2-dimethylpropyl)-3H-imidazo[4,5-b]pyridin-2-amine dimethanesulfonate; 5-[2-Tert-butyl-5-(4-fluoro-phenyl)-1H-imidazol-4-yl]-3-(2,2-dimethyl-propyl)-3H-imidazo[4,5-b]pyridin-2-ylamine dimethanesulfonate; 5-(2-(Tert-butyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)-3-(2,2-dimethylpropyl)-3H-imidazo (4,5-b)pyridin-2-amine methanesulfonate; 5-(2-Tert-butyl-4-(4-fluorophenyl)-1H-imidazol-5-yl)-3-neopentyl-3H-imidazo[4,5-b]pyridin-2-amine dimethanesulfonate
CAS No.:
862507-23-1
Compound CID:
11570805
Formula:
C24H29FN6·2CH4O3S
Formula Weight:
612.74
Specification
Targets & IC50:
p38α: 7 nM
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Ralimetinib dimesylate has strong anti-tumor activity and can be used in studies of non-small cell lung cancer and other solid tumor diseases.
Library Information
Targets:
Autophagy; p38 MAPK; Apoptosis
Receptors:
Apoptosis; Autophagy; p38 MAPK; p38α
Pathways:
Autophagy; Apoptosis; MAPK
Plate Number:
AOCL-5
Plate Location:
b2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
27.5 mg/mL; 44.88 mM
ALogP:
5.117
HBA_Count:
3
HBD_Count:
2
Rotatable Bond:
5





