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SIRT1 Blocking Peptide (C-EITEKPPRTQKE)
Cat. No.:
OB0526-WX6
Origin:
Synthetic
Conjugation:
Unconjugate
Species Reactivity:
Human; Mouse; Rat; Dog
Size:
Add to basket
Product Overview
Description:
SIRT1 Blocking Peptide (C-EITEKPPRTQKE) is a custom synthetic control peptide tailored to match antibodies targeting this specific regional sequence of SIRT1. It serves as a robust negative control in chromatin immunoprecipitation (ChIP), WB, and IHC assays exploring epigenetic regulation and cell longevity.
Sequence:
C-EITEKPPRTQKE
Molecular Weight:
1568.8 Da
Purity:
≥95%
Applications:
Western blotting; ELISA; IHC; IF; Functional Assay; Cell Culture; Binding Assay
Specification
Storage:
Storage at -20°C.
Shipping Condition:
Shipped with ice packs.
Handling Notes:
During shipping, trace amounts of the blocking peptide may adhere to the interior surface of the vial cap. Before opening, it is highly recommended to briefly centrifuge the vial to bring all contents to the bottom.
Target Profile
Full Name:
NAD-dependent protein deacetylase sirtuin-1
Alternative Names:
SIR2L1; SIRT1; Sirtuin 1; SIR2; SIR2alpha; SIR2-like protein 1
Summary:
SIRT1 is a member of the sirtuin family and a homolog of the yeast Sir2 protein. It acts as an intracellular regulator with mono-ADP-ribosyltransferase and deacetylase activity. SIRT1 is often described as a "longevity gene" because it senses cellular energy levels (NAD+) and coordinates epigenetic gene silencing and metabolic adaptation to caloric restriction.