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S7 (LSLITRL)
Cat. No.:
OB0526-WX192
Origin:
Synthetic
Conjugation:
Unconjugate
Size:
Add to basket
Product Overview
Description:
S7 (LSLITRL) is an inhibitory polypeptide that targets interleukin-6 receptor (IL-6R). It selectively binds IL-6R and its A chain, gp80/IL-6RA, thereby blocking downstream signaling. It suppresses IL-6-mediated anti-apoptotic effects, angiogenesis, and VEGF-A expression, inhibits associated cell-survival pathways, and increases the sensitivity of cancer cells to chemotherapeutic agents. It can be investigated in research on cervical cancer, multiple myeloma, Kaposi's sarcoma, prostate cancer, and basal cell carcinoma.
Sequence:
LSLITRL
Formula:
C37H70N10O10
Molecular Weight:
815.01
CAS No.:
853248-13-2
Purity:
≥98%
Applications:
Western blotting; ELISA; IHC; IF; Functional Assay; Cell Culture; Binding Assay
Specification
Storage:
Storage at -80°C.
Shipping Condition:
Shipped with dry ice.
Handling Notes:
During shipping, trace amounts of the peptide may adhere to the interior surface of the vial cap. Before opening, it is highly recommended to briefly centrifuge the vial to bring all contents to the bottom.
