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Lipid 8
Cat. No.:
OB0626WX-3854
Appearance:
Liquid
Purity:
≥95%
Identity:
Confirmed by NMR, TLC, and HPLC.
Size:
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Product Overview
Description:
Lipid 8 is an ionizable cationic lipid optimized for integration into multi-component lipid nanoparticles designed for targeted oncology applications. The ionizable amine core facilitates stable small interfering RNA packaging and responsive intracellular delivery, enabling the targeted down-regulation of mitotic kinases to trigger apoptotic cascades within malignant hematopoietic lineages.
Synonyms:
4-(dimethylamino)-butanoic acid, 2-[di-(9Z,12Z)-9,12-octadecadien-1-ylamino]ethyl ester; 2-(Di((9Z,12Z)-octadeca-9,12-dien-1-yl)amino)ethyl 4-(dimethylamino)butanoate; 2-[bis[(9Z,12Z)-octadeca-9,12-dienyl]amino]ethyl 4-(dimethylamino)butanoate; 2226547-25-5
CAS No.:
2226547-25-5
Compound CID:
139508899
Formula:
C44H82N2O2
Formula Weight:
671.1
Specification
Solubility in Other Solvents:
Methyl acetate: 25 mg/mL
Storage:
Storage at -20°C.
Applications:
Lipid 8 serves as a research lipid for developing lipid nanoparticle delivery systems. It supports optimization of lipid formulations, investigation of ionizable lipid structure–activity relationships, and evaluation of nucleic acid delivery efficiency and nanoparticle properties.
