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N-[1-(2,3-Di(9-octadecenoyloxy)propyl]-N,N,N-trimethylammonium (chloride)
Cat. No.:
OB0626WX-3872
Appearance:
Solid
Purity:
≥98% (mixture of isomers)
Identity:
Confirmed by NMR, TLC, IR, and HPLC.
Size:
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Product Overview
Description:
N-[1-(2,3-Di(9-octadecenoyloxy)propyl]-N,N,N-trimethylammonium is a defined isomeric mixture of high-purity cationic lipids comprising N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium and N-[1-(2,3-dielaidoyloxy)propyl]-N,N,N-trimethylammonium. This quaternary ammonium formulation presents a permanently positive surface charge, serving as a classical benchmark matrix for achieving high-density electrostatic nucleic acid binding.
Synonyms:
N,N,N-trimethyl-2,3-bis(9-octadecen-1-yloxy)-1-propanaminium, monochloride; 104872-42-6; 1,2-di-O-octadecenyl-3-trimethylammonium propane (chloride salt); N,N,N-Trimethyl-2,3-bis(octadec-9-en-1-yloxy)propan-1-aminium chloride; (E)-DOTMA; N-[1-(2,3-Dioleyloxy)propyl]-N,N,N-trimethylammonium Chloride; 2,3-bis[(E)-octadec-9-enoxy]propyl-trimethyl-ammonium chloride; 2,3-bis[(E)-octadec-9-enoxy]propyl-trimethylazanium chloride
CAS No.:
104872-42-6
Compound CID:
16730297
Formula:
C42H84NO2 • Cl
Formula Weight:
670.6
Specification
Solubility in Ethanol:
30 mg/mL
Solubility in Other Solvents:
PBS: 10 mg/mL
Storage:
Storage at -20°C.
Applications:
N-[1-(2,3-Di(9-octadecenoyloxy)propyl]-N,N,N-trimethylammonium (chloride) serves as a cationic lipid for liposome preparation and lipid-mediated nucleic acid delivery research. It supports membrane interaction studies, formulation optimization, lipid assembly characterization, and evaluation of cationic lipid delivery systems.