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IGF2 Blocking Peptide (ETYCATPAKSERD)
Cat. No.:
OB0526-WX69
Origin:
Synthetic
Conjugation:
Unconjugate
Species Reactivity:
Human; Mouse; Rat; Dog; Porcine; Cow
Size:
Add to basket
Product Overview
Description:
IGF2 Blocking Peptide (ETYCATPAKSERD) is a synthetic peptide matching a specific immunogenic sequence within the IGF2 protein. When used in antibody pre-incubation experiments, it selectively neutralizes compatible anti-IGF2 antibodies and provides a reliable means of validating target-specific immunoreactivity. This peptide serves as an effective negative control in protein detection studies.
Sequence:
ETYCATPAKSERD
Molecular Weight:
1484.6 Da
Purity:
≥95%
Applications:
Western blotting; ELISA; IHC; IF; Functional Assay; Cell Culture; Binding Assay
Specification
Storage:
Storage at -20°C.
Shipping Condition:
Shipped with ice packs.
Handling Notes:
During shipping, trace amounts of the blocking peptide may adhere to the interior surface of the vial cap. Before opening, it is highly recommended to briefly centrifuge the vial to bring all contents to the bottom.
Target Profile
Full Name:
Insulin-like growth factor 2
Alternative Names:
IGF2; Insulin-like growth factor II; IGF-II; Somatomedin-A; T3M-11-derived growth factor; IGF-2
Summary:
Insulin-like growth factor 2 (IGF2) is a peptide growth factor belonging to the insulin family and plays an important role in growth and development. Its expression is regulated by genomic imprinting, with expression generally occurring from the paternal allele. Epigenetic alterations at the IGF2 locus have been associated with developmental and growth-related disorders, including Wilms tumor, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. The INS-IGF2 read-through transcript overlaps the INS gene at its 5′ region and IGF2 at its 3′ region. Alternative transcript variants encoding different isoforms have been reported.
