ADRB3 Blocking Peptide (C-EARQSPPLNRFD)

Cat. No.: OB0526-WX58

Origin: Synthetic

Conjugation: Unconjugate

Species Reactivity: Mouse

Size:

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Product Overview

Description: ADRB3 Blocking Peptide (C-EARQSPPLNRFD) is an epitope-specific synthetic peptide developed for use with compatible ADRB3 antibodies. By selectively blocking antibody binding to the corresponding ADRB3 sequence, it helps researchers verify target-specific immunoreactivity and distinguish genuine signals from background staining. The peptide provides a valuable control for antibody validation studies.

Sequence: C-EARQSPPLNRFD

Molecular Weight: 1548.7 Da

Purity: ≥95%

Applications: Western blotting; ELISA; IHC; IF; Functional Assay; Cell Culture; Binding Assay

Specification

Storage: Storage at -20°C.

Shipping Condition: Shipped with ice packs.

Handling Notes: During shipping, trace amounts of the blocking peptide may adhere to the interior surface of the vial cap. Before opening, it is highly recommended to briefly centrifuge the vial to bring all contents to the bottom.

Target Profile

Full Name: Adrenoceptor Beta 3

Alternative Names: ADRB3; BETA3AR; Beta-3 Adrenergic Receptor; ADRB3R; Beta-3 Adrenoreceptor; B3AR; Adrenergic, Beta-3-, Receptor; Adrb3r; B3bar

Gene ID: 11556

Uniprot ID: P25962

Summary: Beta-3 adrenergic receptor (ADRB3) is a G protein-coupled receptor that responds to catecholamines and regulates adenylyl cyclase activity through G protein signaling. It is expressed predominantly in adipose tissue, where it contributes to the regulation of lipolysis and thermogenesis. Genetic polymorphisms in ADRB3 and other beta-adrenergic receptor subtypes have been investigated for associations with obesity and body weight-related traits. ADRB3 is widely studied in research on energy expenditure, adipose tissue function, and metabolic regulation.

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