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IAJD93
Cat. No.:
OB0626WX-3816
Appearance:
Liquid
Purity:
≥95%
Identity:
Confirmed by NMR and HPLC.
Size:
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Product Overview
Description:
IAJD93 is an ionizable amphiphilic Janus dendrimer boasting a defined pKa of 6.25, developed as a high-performance, non-viral vector system for nucleic acid transport. This structured amphiphile undergoes spontaneous electrostatic co-assembly with transcript payloads to construct organized dendrimersome nanoparticles, optimizing endosomal escape and systemic trafficking kinetics to successfully deliver encapsulated messenger RNA into hepatic, splenic, pulmonary, and lymph node tissue architectures.
Synonyms:
3-((2-ethylhexyl)oxy)-2,2-bis(((2-ethylhexyl)oxy)methyl)propyl 4-(4-(2-hydroxyethyl)piperazin-1-yl)butanoate; Ionizable Amphiphilic Janus Dendrimer 93; 3076338-50-3; IAJD 93; IAJD 294
CAS No.:
3076338-50-3
Compound CID:
170916129
Formula:
C39H78N2O6
Formula Weight:
671
Specification
Solubility in Ethanol:
Soluble
Solubility in Other Solvents:
Soluble in chloroform and methanol.
Storage:
Storage at -20°C.
Applications:
IAJD93 serves as a research lipid for developing and optimizing lipid nanoparticle formulations. It supports comparative evaluation of ionizable lipid structures, formulation screening, nucleic acid delivery studies, and investigations of lipid composition–dependent nanoparticle performance.
