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Docetaxel polymeric nanoparticles
Cat. No.:
OB0626WX-3817
Appearance:
Solid
Size:
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Product Overview
Description:
Docetaxel polymeric nanoparticles are highly uniform, multi-component lipid-based nanocarriers measuring 15 to 20 nm in size, synthesized through the co-assembly of tocofersolan, poloxanlene, and disaccharide stabilizers. This pre-formulated macromolecular matrix encapsulates a semi-synthetic microtubule-stabilizing derivative of paclitaxel, providing a specialized delivery architecture that enhances hydrophobic drug solubility, protects the therapeutic cargo against metabolic degradation, modulates release kinetics, and eliminates the vehicle-induced cellular toxicity associated with conventional organic solvent matrices.
Synonyms:
Docetaxel PNPs; Docetaxel Polymer-based Nanoparticles; DTX PNPs; RP 56976 PNPs
Specification
Storage:
Storage at -20°C.
Applications:
Docetaxel polymeric nanoparticles serve as a nanoparticle formulation for investigating polymer-based drug delivery strategies and controlled release systems. They support studies of nanoparticle physicochemical properties, formulation optimization, cellular uptake, and preclinical evaluation of nanocarrier performance while providing a model platform for polymeric drug delivery research.