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OF-02
Cat. No.:
OB0626WX-3904
Appearance:
Liquid
Purity:
≥90% (mixture of isomers)
Identity:
Confirmed by NMR, TLC, and IR.
Size:
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Product Overview
Description:
OF-02 is an ionizable cationic amino lipid optimized as a primary structural scaffold within multi-lipid nanoparticle assemblies dedicated to transcript transport. This ionizable framework provides robust protection for large nucleotides during systemic circulation, directing the localization of encapsulated payloads to hepatic centers to drive high-efficiency expression and elevated serum levels of metabolic regulatory proteins.
Synonyms:
3,6-bis[4-[bis[(9Z,12Z)-2-hydroxy-9,12-octadecadien-1-yl]amino]butyl]-2,5-piperazinedione; 3,6-bis(4-(bis((9z,12z)-2-hydroxyoctadeca-9,12-dien-1-yl)amino)butyl)piperazine-2,5-dione; 1883431-67-1
CAS No.:
1883431-67-1
Compound CID:
132594335
Formula:
C84H152N4O6
Formula Weight:
1314.1
Specification
Solubility in Ethanol:
10 mg/mL
Storage:
Storage at -20°C.
Applications:
OF-02 serves as a synthetic lipid for lipid nanoparticle formulation research and supports studies of lipid-mediated nucleic acid delivery. It facilitates optimization of formulation composition, physicochemical characterization, and evaluation of lipid structure–activity relationships.
