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Glucosamine cholesterol
Cat. No.:
OB0626WX-3831
Appearance:
Solid
Purity:
≥95%
Identity:
Confirmed by NMR, TLC, and HPLC.
Size:
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Product Overview
Description:
Glucosamine cholesterol is an amphiphilic, carbohydrate-modified sterol conjugate engineered to incorporate a hydrophilic glucosamine domain linked directly to a rigid cholesterol anchor. When integrated into lipid nanoparticles, this molecule creates a stable, ordered bilayer with the sugar headgroup facing outward to exploit glucose transporter-mediated cellular internalization, subsequently delivering pro-apoptotic lipid or chemotherapeutic payloads to selectively reduce tumor volumes, eliminate hypoxic cancer stem cell populations, and enrich tumor-associated cytotoxic T cell networks.
Synonyms:
2-[[4-[(3β)-cholest-5-en-3-yloxy]-1,4-dioxobutyl]amino]-2-deoxy-D-glucopyranose; 1257309-90-2
CAS No.:
1257309-90-2
Compound CID:
171038221
Formula:
C37H61NO8
Formula Weight:
647.9
Specification
Storage:
Storage at -20°C.
Applications:
Glucosamine cholesterol serves as a cholesterol-based lipid derivative for investigating membrane engineering and lipid nanoparticle design. It supports the development of functional lipid assemblies, lipid conjugation strategies, formulation optimization, and studies of membrane-associated delivery systems.
