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BIX02189
Cat. No.:
OB0225LY-0205
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR and HPLC.
Size:
Product Overview
Description:
BIX02189 is a small molecule inhibitor that specifically targets histone methyltransferases.
Synonym:
BIX 02189; 1094614-85-3; BIX-02189; (Z)-3-((3-((Dimethylamino)methyl)phenylamino)(phenyl)methylene)-N, N-dimethyl-2-oxoindoline-6-carboxamide; (Z)-3-(((3-((Dimethylamino)methyl)phenyl)amino)(phenyl)methylene)-N, N-dimethyl-2-oxoindoline-6-carboxamide; 3-[N-[3-[(Dimethylamino)methyl]phenyl]-C-phenylcarbonimidoyl]-2-hydroxy-N, N-dimethyl-1H-indole-6-carboxamide; BIX02189 (BIX 02189; (3Z)-3-[[3-[(Dimethylamino)methyl]anilino]-phenylmethylidene]-N, N-dimethyl-2-oxo-1H-indole-6-carboxamide
CAS No.:
1094614-85-3
Compound CID:
135659062
Formula:
C27H28N4O2
Formula Weight:
440.54
Specification
Relative Density:
1.230 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
BIX02189 can be used to study epigenetic regulation and its role in development, growth and disease.
Library Information
Targets:
MEK; TGF-beta/Smad; ERK
Receptors:
ERK5; MEK1; MEK2; MEK5; TGFβR1
Pathways:
Stem cells; MAPK
Plate Number:
AOCL-3
Plate Location:
e9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
50 mg/mL; 113.5 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
74 mg/mL; 168 mM
