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Autogramin-1
Cat. No.:
OB0225LY-0348
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Product Overview
Description:
Autogramin-1 is an important compound that inhibits autophagy induced by mTORC1 inhibition (Rapamycin; IC50: 0.44 μM) or starvation.
Synonym:
2375541-73-2; tert-Butyl 2-[(2,4-dioxo-3-propyl-1H-quinazoline-7-carbonyl)amino]-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-5-carboxylate; tert-Butyl 2-(2,4-dioxo-3-propyl-1,2,3,4-tetrahydroquinazoline-7-carboxamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
CAS No.:
2375541-73-2
Compound CID:
138106864
Formula:
C23H27N5O5S
Formula Weight:
485.56
Specification
Relative Density:
1.359 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Autogramin-1 can be used in signaling studies or play an important role in cell communication studies.
Library Information
Targets:
PI3K/Akt/mTOR pathway
Receptors:
mTORC1
Pathways:
Autophagy; PI3K/Akt/mTOR signaling
Plate Number:
AOCL-5
Plate Location:
e2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
