APY0201

Cat. No.: 0225LY-0779

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and LC-MS.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: APY0201 is a highly specific, ATP-competitive inhibitor of PIKfyve (IC50: 5.2 nM) that halts the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3,5)P2.

Synonym: 1232221-74-7; (E)-4-(5-(2-(3-methylbenzylidene)hydrazinyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)morpholine; N-[(E)-(3-methylphenyl)methylideneamino]-7-morpholin-4-yl-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-5-amine; 4-(5-(2-(3-Methylbenzylidene)hydrazinyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)morpholine

CAS No.: 1232221-74-7

Compound CID: 56927660

Formula: C₂₃H₂₃N₇

Formula Weight: 413.48

Specification

Targets&IC50: PIKfyve: 5.2 nM

Relative Density: 1.33 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: APY0201 can be used in virology studies to investigate the potent inhibition of PIKfyve and its role in blocking infectious viral pathways.