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KI696
Cat. No.:
0225LY-1448
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, and LC-MS.
Size:
Add to basket
Product Overview
Description:
KI696 is a high-affinity chemical probe used to effectively block the protein-protein interaction between NRF2 and Keap1.
Synonym:
1799974-70-1; (3s)-3-(7-Methoxy-1-Methyl-1h-Benzo[d][1,2,3]triazol-5-Yl)-3-(4-Methyl-3-(((R)-4-Methyl-1,1-Dioxido-3,4-Dihydro-2h-Benzo[b][1,4,5]oxathiazepin-2-Yl)methyl)phenyl)propanoic Acid; KI-696; (3S)-3-(7-methoxy-1-methylbenzotriazol-5-yl)-3-[4-methyl-3-[[(4R)-4-methyl-1,1-dioxo-3,4-dihydro-5,1lambda6,2-benzoxathiazepin-2-yl]methyl]phenyl]propanoic acid
CAS No.:
1799974-70-1
Compound CID:
118170767
Formula:
C28H30N4O6S
Formula Weight:
550.63
Specification
Relative Density:
1.39 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
KI696 can be used in molecular biology to investigate the potent and selective disruption of the Keap1-Nrf2 interaction.
Library Information
Target:
Nrf2
Receptor:
Keap1-Nrf2 Interface
Pathways:
Oxidative stress; Immunology/Inflammation; Chromatin/Epigenetic
Plate Number:
AOCL-19
Plate Location:
e11
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
150 mg/mL; 272.42 mM
