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Entrectinib
Cat. No.:
OB0225LY-0374
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR and HPLC.
Size:
Product Overview
Description:
Entrectinib is a multi-target inhibitor that targets specific kinases with favorable biological activity.
Synonym:
RXDX-101; NMS-E628; 1108743-60-7; Rozlytrek; N-(5-(3,5-Difluorobenzyl)-1H-indazol-3-yl)-4-(4-methylpiperazin-1-yl)-2-((tetrahydro-2H-pyran-4-yl)amino)benzamide; N-[5-[(3,5-Difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methylpiperazin-1-yl)-2-(oxan-4-ylamino)benzamide; Benzamide, N-(5-((3,5-difluorophenyl)methyl)-1H-indazol-3-yl)-4-(4-methyl-1-piperazinyl)-2-((tetrahydro-2H-pyran-4-yl)amino)-
CAS No.:
1108743-60-7
Compound CID:
25141092
Formula:
C31H34F2N6O2
Formula Weight:
560.64
Specification
Relative Density:
1.340 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Entrectinib can be used to study the role of gene rearrangements in cancer or play an important role in cell signaling studies.
Library Information
Targets:
Kinases
Receptors:
ALK; ROS; Trk receptor; TrkA; TrkB; TrkC; ROS1
Pathways:
Immunology/Inflammation; Angiogenesis; Autophagy; Tyrosine kinase/adaptors
Plate Number:
AOCL-5
Plate Location:
g9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
50 mg/mL; 89.18 mM
Water Max Solubility:
<1 mg/mL
Ethanol Max Solubility:
67 mg/mL; 119.5 mM
Solubility:
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 10 mg/mL (17.84 mM)
