AdipoUpX™ Human MRAP2 MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human MRAP2 MSCV Particle (Overexpression) is a high-titer, ready-to-use MSCV retroviral particle designed for the stable overexpression of the human MRAP2 gene. MRAP2 is a critical modulator of MC4R signaling, essential for the central regulation of appetite and energy expenditure. Its structure is optimized for stem cells and different mammalian cell lines, providing stable integration for longitudinal metabolic studies. To guarantee reliable results, all products pass through rigorous quality control validation for performance and purity.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: MRAP2

Full Name: Melanocortin 2 receptor accessory protein 2

Gene Symbol: C6orf117; bA51G5.2

Gene ID: 112609

RefSeq ID-1: NP_001333470.1

RefSeq ID-2: NM_001346541.1

Summary: MRAP2 encodes a protein that regulates melanocortin receptor activity, affecting both receptor trafficking and ligand-mediated activation. Loss of function in MRAP2 leads to severe obesity in mice, and similar mutations in humans are associated with extreme obesity, highlighting its role in energy balance regulation.

AdipoUpX™ Human MRAP2 MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

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