AdipoUpX™ Human MC3R MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human MC3R MSCV Particle (Overexpression) is a professionally engineered vector particle providing efficient and stable overexpression of human MC3R. This receptor plays a distinct role in regulating feeding efficiency and the timing of energy rheostasis. Its MSCV structure is optimized specifically for hematopoietic and stem cell types, etc., facilitating the establishment of reliable, stable cell lines for GPCR signaling research. The viral system offers high flexibility for customizing functional components and is backed by comprehensive quality control to ensure data integrity.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: MC3R

Full Name: Melanocortin 3 receptor

Gene Symbol: MC3; OB20; OQTL; BMIQ9; MC3-R

Gene ID: 4159

RefSeq ID-1: NP_063941.3

RefSeq ID-2: NM_019888.3

Summary: The MC3R gene encodes a melanocortin receptor belonging to the G protein–coupled receptor superfamily. This receptor responds to melanocortin peptides, including melanocyte-stimulating hormone and adrenocorticotropic hormone, and is expressed in multiple tissues beyond classical endocrine targets. Experimental studies in MC3R-deficient mice reveal increased adiposity despite reduced caloric intake, suggesting a key role in energy expenditure and metabolic efficiency. In humans, genetic variants of MC3R are associated with an elevated risk of obesity.

AdipoUpX™ Human MC3R MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

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