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UCP2 Blocking Peptide (C-DSVKQFYTKGSEH)
Cat. No.:
OB0526-WX3
Origin:
Synthetic
Conjugation:
Unconjugate
Species Reactivity:
Human; Mouse; Rat; Dog
Size:
Add to basket
Product Overview
Description:
UCP2 Blocking Peptide (C-DSVKQFYTKGSEH) is a highly purified synthetic peptide matching the specific epitope of the UCP2 antibody. Blocking the antibody's antigen-binding sites, it enables researchers to rigorously verify specific mitochondrial uncoupling protein-2 expression in obesity, oxidative stress, and metabolic syndrome research.
Sequence:
C-DSVKQFYTKGSEH
Molecular Weight:
1627.7 Da
Purity:
≥95%
Applications:
Western blotting; ELISA; IHC; IF; Functional Assay; Cell Culture; Binding Assay
Specification
Storage:
Storage at -20°C.
Shipping Condition:
Shipped with ice packs.
Handling Notes:
During shipping, trace amounts of the blocking peptide may adhere to the interior surface of the vial cap. Before opening, it is highly recommended to briefly centrifuge the vial to bring all contents to the bottom.
Target Profile
Full Name:
Uncoupling protein 2
Alternative Names:
Mitochondrial uncoupling protein 2; UCP2; SLC25A8; UCPH; Uncoupling protein-2; BMIQ4
Summary:
UCP2 is a crucial member of the mitochondrial uncoupling protein (UCP) family, functioning within the inner mitochondrial membrane. It mediates the "mitochondrial proton leak," a process that dissipates the proton gradient as heat, thereby uncoupling oxidative phosphorylation from ATP generation. Expressed broadly, particularly highly in skeletal muscle, UCP2 acts to reduce the mitochondrial membrane potential and may play a protective role against reactive oxygen species (ROS). Its systemic role in nonshivering thermogenesis and metabolic efficiency positions it as a significant candidate in research concerning the genetic basis of obesity and diabetes.
