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Tetramyristoylcardiolipin, ammonium salt
Cat. No.:
OB0626WX-3913
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, TLC, and HPLC.
Size:
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Product Overview
Description:
Tetramyristoylcardiolipin is an anionic phospholipid possessing four fully saturated, long-chain myristic acid hydrophobic tails linked to a dual-phosphatidylglycerol core architecture. This specialized lipid acts as a potent modulator of membrane thermodynamics, inducing concentration-dependent elevations in the gel-to-liquid crystalline phase transition temperature of lipid bilayers and forming highly organized lipid-protein nanodisks that undergo ion-stimulated non-bilayer transformations.
Synonyms:
Tetradecanoic acid, 1,1′,1′′,1′′′-[(2R,14R)-5,8,11-trihydroxy-5,11-dioxido-4,6,10,12-tetraoxa-5,11-diphosphapentadecane-1,2,14,15-tetrayl] ester, diammonium salt; TMCL; Tetramyristoylcardiolipin (ammonium salt); 1',3'-bis[1,2-dimyristoyl-sn-glycero-3-phospho]-sn-glycerol (ammonium salt); Diazanium;[3-[[(2R)-2,3-di(tetradecanoyloxy)propoxy]-oxidophosphoryl]oxy-2-hydroxypropyl] [(2R)-2,3-di(tetradecanoyloxy)propyl] phosphate; 63988-20-5
CAS No.:
63988-20-5
Compound CID:
166603949
Formula:
C65H124O17P2 • 2NH4
Formula Weight:
1275.7
Specification
Solubility in Other Solvents:
Chloroform: 10 mg/mL
Storage:
Storage at -20°C.
Applications:
Tetramyristoylcardiolipin, ammonium salt serves as a defined cardiolipin molecular species for membrane biochemistry, mitochondrial lipid research, and lipidomics applications. It supports preparation of model membrane systems, analytical method development, structural characterization of cardiolipins, and investigation of cardiolipin-dependent membrane organization and lipid–protein interactions.
