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TCS 1102
Cat. No.:
0225LY-1334
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
TCS 1102 serves as an effective dual antagonist for orexin receptors, with Ki values of 3 nM and 0.2 nM for OX1 and OX2, respectively.
Synonym:
DORA-1; 916141-36-1; (2S)-1-[2-(1-methylbenzimidazol-2-yl)sulfanylacetyl]-N-(2-phenylphenyl)pyrrolidine-2-carboxamide; TCS1102; BBAC; TCS-1102; (S)-N-([1,1'-Biphenyl]-2-yl)-1-(2-((1-methyl-1H-benzo[d]imidazol-2-yl)thio)acetyl)pyrrolidine-2-carboxamide
CAS No.:
916141-36-1
Compound CID:
11960895
Formula:
C27H26N4O2S
Formula Weight:
470.59
Specification
Targets&IC50:
OX2: 0.2nM; OX1: 3 nM
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
TCS 1102 can be used in neuroscience research to investigate the dual antagonism of orexin OX1 and OX2 receptors.
Library Information
Target:
OX receptor
Receptor:
OX1R; OX2R
Pathways:
GPCR signaling; Neuronal signaling
Plate Number:
AOCL-18
Plate Location:
a11
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
50 mg/mL; 106.25 mM
Ethanol Max Solubility:
100 mM
