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GANT 61
Cat. No.:
OB0225LY-0497
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR and HPLC.
Size:
Product Overview
Description:
GANT 61 is a small molecule inhibitor that targets GLI transcription factors and is able to inhibit the activity of the Hedgehog pathway.
Synonym:
NSC 136476; GANT61; 500579-04-4; 2,2'-((2-(Pyridin-4-yl)dihydropyrimidine-1,3(2H,4H)-diyl)bis(methylene))bis(N, N-dimethylaniline); 2-[[3-[[2-(Dimethylamino)phenyl]methyl]-2-pyridin-4-yl-1,3-diazinan-1-yl]methyl]-N, N-dimethylaniline
CAS No.:
500579-04-4
Compound CID:
421610
Formula:
C27H35N5
Formula Weight:
429.6
Specification
Relative Density:
1.134 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
GANT 61 can be used to study the mechanisms of tumorigenesis and development or play an important role in experiments to intervene in the Hedgehog signaling pathway.
Library Information
Targets:
Hedgehog/Smoothened
Receptors:
Gli; GLI1
Pathways:
GPCR/G protein; Autophagy; Stem cells
Plate Number:
AOCL-7
Plate Location:
d9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
4.3 mg/mL; 10 mM
Ethanol Max Solubility:
43 mg/mL; 100 mM
