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SIRT1 Blocking Peptide (C-EKPQEVQTSRNVES)
Cat. No.:
OB0526-WX5
Origin:
Synthetic
Conjugation:
Unconjugate
Species Reactivity:
Human; Mouse
Size:
Add to basket
Product Overview
Description:
SIRT1 Blocking Peptide (C-EKPQEVQTSRNVES) is a sequence-specific synthetic peptide corresponding to a distinct epitope of the human SIRT1 protein. It is optimized for pre-incubation with compatible SIRT1 antibodies to conclusively demonstrate antibody specificity and differentiate genuine sirtuin-1 signals from non-specific bands.
Sequence:
C-EKPQEVQTSRNVES
Molecular Weight:
1747.9 Da
Purity:
≥95%
Applications:
Western blotting; ELISA; IHC; IF; Functional Assay; Cell Culture; Binding Assay
Specification
Storage:
Storage at -20°C.
Shipping Condition:
Shipped with ice packs.
Handling Notes:
During shipping, trace amounts of the blocking peptide may adhere to the interior surface of the vial cap. Before opening, it is highly recommended to briefly centrifuge the vial to bring all contents to the bottom.
Target Profile
Full Name:
NAD-dependent protein deacetylase sirtuin-1
Alternative Names:
SIR2L1; SIRT1; Sirtuin 1; SIR2; SIR2alpha; SIR2-like protein 1
Summary:
SIRT1 is a member of the sirtuin family and a homolog of the yeast Sir2 protein. It acts as an intracellular regulator with mono-ADP-ribosyltransferase and deacetylase activity. SIRT1 is often described as a "longevity gene" because it senses cellular energy levels (NAD+) and coordinates epigenetic gene silencing and metabolic adaptation to caloric restriction.
