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SH5-07 (SH-5-07)
Cat. No.:
OB0225WX-2715
Appearance:
Solid
Purity:
≥97%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
SH5-07 is a hydroxamic acid-derived inhibitor of STAT3 that exerts its biological effects by suppressing the STAT3 signaling axis in various cellular models.
Synonym:
SH5-07; 1456632-41-9; SH5-07 (SH-5-07); 4-(N-(4-Cyclohexylbenzyl)-2-(2,3,4,5,6-pentafluoro-N-methylphenylsulfonamido)acetamido)-N-hydroxybenzamide; 4-[[(4-Cyclohexylphenyl)methyl][2-[methyl[(2,3,4,5,6-pentafluorophenyl)sulfonyl]amino]acetyl]amino]-N-hydroxy-benzamide; SH5 07; (SH-5-07; 4-[(4-cyclohexylphenyl)methyl-[2-[methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]amino]-N-hydroxybenzamide; 4-(N-(4-Cyclohexylbenzyl)-2-((2,3,4,5,6-pentafluoro-N-methylphenyl)sulfonamido)acetamido)-N-hydroxybenzamide; 4-[[(4-Cyclohexylphenyl)methyl][2-[methyl[(2,3,4,5,6-pentafluorophenyl)sulfonyl]amino]acetyl]amino]-N-hydroxybenzamide; 4-{N-[(4-cyclohexylphenyl)methyl]-2-(N-methyl-2,3,4,5,6-pentafluorobenzenesulfonamido)acetamido}-N-hydroxybenzamide
CAS No.:
1456632-41-9
Compound CID:
72550504
Formula:
C29H28F5N3O5S
Formula Weight:
625.61
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
SH5-07 is utilized in signal transduction research as a specialized inhibitor of STAT3 to investigate the disruption of transcription factor dimerization and its impact on suppressing oncogenic growth.
Library Information
Target:
STAT
Receptor:
STAT3
Pathways:
JAK/STAT
Plate Number:
L6700-09
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
100 mg/mL; 159.84 mM
Ethanol Max Solubility:
100 mg/mL
ALogP:
5.606
HBA_Count:
4
HBD_Count:
1
Rotatable Bond:
9





