RXRB Blocking Peptide (CRDGMGDSGRDSRSP)

Cat. No.: OB0526-WX24

Origin: Synthetic

Conjugation: Unconjugate

Species Reactivity: Human; Mouse; Rat; Dog; Porcine; Cow

Size:

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Product Overview

Description: RXRB Blocking Peptide (CRDGMGDSGRDSRSP) is a synthetic peptide representing a defined antigenic sequence of the retinoid X receptor beta (RXRB) protein. It is designed for pre-incubation with compatible RXRB antibodies to selectively block specific antigen recognition. This reagent supports antibody validation procedures and helps ensure reliable interpretation of immunoassay results.

Sequence: CRDGMGDSGRDSRSP

Molecular Weight: 1582.6 Da

Purity: ≥95%

Applications: Western blotting; ELISA; IHC; IF; Functional Assay; Cell Culture; Binding Assay

Specification

Storage: Storage at -20°C.

Shipping Condition: Shipped with ice packs.

Handling Notes: During shipping, trace amounts of the blocking peptide may adhere to the interior surface of the vial cap. Before opening, it is highly recommended to briefly centrifuge the vial to bring all contents to the bottom.

Target Profile

Full Name: Retinoid X Receptor Beta

Alternative Names: RXRB; Retinoic acid receptor RXR-beta; Nuclear receptor subfamily 2 group B member 2; NR2B2

Summary: Retinoid X receptor beta (RXRβ) is a member of the nuclear receptor family involved in regulating gene transcription in response to retinoid-related signaling. It forms homodimers and heterodimers with other nuclear receptors, including retinoic acid, thyroid hormone, and vitamin D receptors, thereby influencing DNA binding and transcriptional activity at their respective response elements. The RXRβ gene is located within the major histocompatibility complex (MHC) class II region on chromosome 6, and alternative transcript variants encoding multiple isoforms have been described.

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