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PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl)-d62, sodium salt
Cat. No.:
OB0626WX-2786
Appearance:
Lyophilized powder
Purity:
≥99% (deuterated forms, d1-d62)
Size:
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Product Overview
Description:
PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl)-d62 is a highly deuterated, stable isotope-labeled internal standard engineered for the precise quantitative determination of symmetric dipalmitoyl phosphatidylinositol-3,4,5-trisphosphate using chromatography-mass spectrometry. The native phosphoinositide acts as a critical membrane anchor that recruits signaling proteins containing pleckstrin homology domains, modulating cytoskeletal rearrangements and vesicular trafficking while exhibiting full resistance to phosphoinositide-specific phospholipase C cleavage.
Labeling:
Stable isotope-labeled
Synonyms:
1-(1,2R-dihexadecanoyl (2,2’,3,3’,4,4’,5,5’,6,6’,7,7’,8,8’,9,9’,10,10’,11,11’,12,12’,13,13’,14,14’,15,16,16,16-d62)phosphatidyl)inositol-3,4,5-trisphosphate, tetrasodium salt; DPPI-3,4,5-P3-d62; Phosphatidylinositol-3,4,5-trisphosphate C-16-d62; PI(3,4,5)P3 (16:0/16:0)-d62; PIP3[3',4',5'](16:0/16:0)-d62
Formula:
C41H16D62O22P4 • 4Na
Formula Weight:
1201.3
Specification
Solubility in Other Solvents:
Water: 10 mg/mL
Storage:
Storage at -20°C.
Applications:
PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl)-d62, sodium salt serves as an isotopically labeled phosphoinositide reference standard for quantitative lipidomics and phosphoinositide analysis. It supports LC-MS/MS quantification, isotope dilution workflows, analytical calibration, and structural characterization of phosphorylated membrane lipids.
