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PGF2α ethyl amide
Cat. No.:
OB0626WX-3439
Appearance:
Liquid
Purity:
≥98%
Identity:
Confirmed by TLC and HPLC.
Size:
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Product Overview
Description:
PGF2α ethyl amide is a synthetic eicosanoid analogue in which the native C-1 terminal carboxyl group is modified to an N-ethyl amide structure, functioning as a stable, uncharged prostanoid prodrug. This derivative exhibits heavily shifted, extended hydrolysis pharmacokinetics compared to traditional ester configurations, undergoing steady enzymatic conversion within tissue matrices to liberate the active free acid and drive standard F-series prostanoid responses.
Synonyms:
N-ethyl-9α,11α,15S-trihydroxy-prosta-5Z,13E-dien-1-amide; Dinoprost ethyl amide; PGF2α-NEt; N-Ethyl-9alpha, 11alpha, 15S-trihydroxy-prosta-5Z, 13E-dien-1-amide; Prostaglandin F2|A ethyl amide; (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]-N-ethylhept-5-enamide; Prostaglandin F2alpha ethyl amide; Prostaglandin F2 ethyl amide; Prostaglandin F2.alpha. ethyl amide; (5Z,9alpha,11alpha,13e,15s)-N-ethyl-9,11,15-trihydroxy-prosta-5,13-dien-1-amide; (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)cyclopentyl)-N-ethylhept-5-enamide; (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]-N-ethyl-hept-5-enamide
CAS No.:
54130-36-8
Compound CID:
52193842
Formula:
C22H39NO4
Formula Weight:
381.6
Specification
Solubility in DMSO:
16 mg/mL
Solubility in Ethanol:
20 mg/mL
Solubility in DMF:
33 mg/mL
Solubility in Other Solvents:
PBS: 300 µg/mL
Storage:
Storage at -20°C.
Applications:
PGF2α ethyl amide serves as a reference compound for prostaglandin analog analysis and lipid mediator research. It supports analytical profiling, structural identification, and comparative studies of modified prostanoid compounds.
