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Palomid 529
Cat. No.:
0225LY-0590
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, and HPLC.
Size:
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Product Overview
Description:
Palomid 529 has been evaluated in clinical trials for the treatment of age-related macular degeneration.
Synonym:
914913-88-5; Palomid-529; 8-(1-Hydroxyethyl)-2-methoxy-3-((4-methoxybenzyl)oxy)-6H-benzo[c]chromen-6-one; 8-(1-Hydroxy-ethyl)-2-methoxy-3-(4-methoxy-benzyloxy)-benzo(c)chromen-6-one; 6H-Dibenzo(b,d)pyran-6-one, 8-(1-hydroxyethyl)-2-methoxy-3-((4-methoxyphenyl)methoxy)-; 8-(1-hydroxyethyl)-2-methoxy-3-((4-methoxyphenyl)methoxy)-6H-benzo(c)chromen-6-one
CAS No.:
914913-88-5
Compound CID:
11998575
Formula:
C24H22O6
Formula Weight:
406.43
Specification
Relative Density:
1.280 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Palomid 529 can be used in ophthalmology and oncology to study the regulation of the Akt/mTOR pathway and its effect on angiogenesis.
Library Information
Target:
mTOR
Receptor:
mTORC1; mTORC2
Pathways:
PI3K/Akt/mTOR signaling; Apoptosis
Plate Number:
AOCL-8
Plate Location:
f5
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
50 mg/mL; 123.02 mM
Ethanol Max Solubility:
<1 mg/mL
ALogP:
4.257
HBA_Count:
5
HBD_Count:
1
Rotatable Bond:
6
