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OTS964 hydrochloride
Cat. No.:
0225LY-1277
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
OTS964 hydrochloride acts as a selective and potent TOPK inhibitor with potential applications in oncology.
Synonym:
1338545-07-5; OTS-964; OTS964 hydrochloride; OTS964; OTS964 (hydrochloride); (R)-9-(4-(1-(dimethylamino)propan-2-yl)phenyl)-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one hydrochloride; 9-[4-[(2R)-1-(dimethylamino)propan-2-yl]phenyl]-8-hydroxy-6-methyl-5H-thieno[2,3-c]quinolin-4-one;hydrochloride
CAS No.:
1338545-07-5
Compound CID:
89675898
Formula:
C23H24N2O2S·HCl
Formula Weight:
428.97
Specification
Targets&IC50:
TOPK: 28 nM
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
OTS964 hydrochloride can be used in cancer research to study the potent inhibition of TOPK and its impact on tumor cell cytokinesis.
Library Information
Target:
TOPK; CDK
Receptor:
TOPK; CDK
Pathways:
Cell cycle/Checkpoint; Apoptosis; MAPK
Plate Number:
AOCL-17
Plate Location:
d4
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
79 mg/mL; 184.16 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
1 mg/mL; 2.33 mM
