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Niclosamide (BAY2353)
Cat. No.:
OB0225WX-2544
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
Niclosamide (BAY2353) is a multifunctional agent that inhibits DNA replication and targets STAT3 with an IC50 of 0.7 μM, showing high specificity for STAT3 phosphorylation over other homologues like STAT1 and STAT5.
Synonym:
Niclocide, NSC 178296; 50-65-7; 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide; Niclocide; Bayluscid; Phenasal; Cestocid; Devermin; Devermine; Helmiantin; Mansonil; Radeverm; Tredemine; Vermitid; Atenase; Fenasal; Iomesan; Iomezan; Lintex; Nasemo; Sagimid; Sulqui; Yomesan; 2',5-Dichloro-4'-nitrosalicylanilide; Mato; Fedal-Telmin; Zestocarp; Bayer 73; BAY 2353; Bayer 2353; Chemagro 2353; Benzamide, 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxy-; Niclosamida; Niclosamidum; Niclosamide (anhydrous); WR 46234; 5-Chloro-2'-chloro-4'-nitrosalicylanilide; Nitrophenyl chlorsalicylamide; Niclosamide, anhydrous; 2-Hydroxy-5-chloro-N-(2-chloro-4-nitrophenyl)benzamide; N-(2-Chloro-4-nitrophenyl)-5-chlorosalicylamide; 2-Chloro-4-nitrophenylamide-6-chlorosalicylic acid; 5-Chloro-N-(2-chloro-4-nitrophenyl) -2-hydroxybenzamide; 5-chloranyl-N-(2-chloranyl-4-nitro-phenyl)-2-oxidanyl-benzamide
CAS No.:
50-65-7
Compound CID:
4477
Formula:
C13H8Cl2N2O4
Formula Weight:
327.12
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Niclosamide (BAY2353) is applied in parasitology and oncology research as an anthelmintic agent to investigate the uncoupling of oxidative phosphorylation and the inhibition of multiple oncogenic signaling pathways.
Library Information
Target:
STAT
Receptor:
STAT3
Pathways:
JAK/STAT
Plate Number:
L6700-05
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
8 mg/mL; 24.46 mM
ALogP:
3.595
HBA_Count:
1
HBD_Count:
2
Rotatable Bond:
3





