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NEIL1 Blocking Peptide (C-DIPSLEPEGTSAS)
Cat. No.:
OB0526-WX52
Origin:
Synthetic
Conjugation:
Unconjugate
Species Reactivity:
Human; Porcine; Cow
Size:
Add to basket
Product Overview
Description:
NEIL1 Blocking Peptide (C-DIPSLEPEGTSAS) is a highly purified synthetic peptide corresponding to the epitope recognized by selected NEIL1 antibodies. Pre-incubation with this peptide effectively blocks antigen-specific antibody interactions and supports rigorous validation of antibody selectivity. It is suitable for use as a negative control in multiple immunodetection formats.
Sequence:
C-DIPSLEPEGTSAS
Molecular Weight:
1433.5 Da
Purity:
≥95%
Applications:
Western blotting; ELISA; IHC; IF; Functional Assay; Cell Culture; Binding Assay
Specification
Storage:
Storage at -20°C.
Shipping Condition:
Shipped with ice packs.
Handling Notes:
During shipping, trace amounts of the blocking peptide may adhere to the interior surface of the vial cap. Before opening, it is highly recommended to briefly centrifuge the vial to bring all contents to the bottom.
Target Profile
Full Name:
Endonuclease 8-like 1
Alternative Names:
NEIL1; Nei Like DNA Glycosylase 1; DNA glycosylase/AP lyase Neil1; DNA-(apurinic or apyrimidinic site) lyase Neil1; Endonuclease VIII-like 1; FPG1; Nei homolog 1 (NEH1); Nei-like protein 1
Summary:
Endonuclease 8-like 1 (NEIL1) is a DNA glycosylase belonging to the Nei endonuclease VIII-like family of DNA repair enzymes. It initiates base excision repair by recognizing and removing damaged DNA bases, particularly oxidized pyrimidines, thereby contributing to the maintenance of genomic integrity. NEIL1 is relevant to studies of oxidative DNA damage, DNA repair mechanisms, and cellular responses to genotoxic stress. Multiple transcript variants encoding distinct isoforms have been reported.
