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Miransertib (ARQ 092) HCl
Cat. No.:
OB0225WX-2753
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
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Product Overview
Description:
Miransertib (ARQ 092) HCl is an orally bioavailable and selective inhibitor of the AKT signaling pathway, characterized by its specific modulation of kinase activity in advanced cellular models.
Synonym:
Miransertib; 1313883-00-9; Miransertib HCl; Miransertib hydrochloride; ARQ 092; Miransertib (hydrochloride); 3-[3-[4-(1-aminocyclobutyl)phenyl]-5-phenylimidazo[4,5-b]pyridin-2-yl]pyridin-2-amine;hydrochloride; 3-(3-(4-(1-aminocyclobutyl)phenyl)-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine hydrochloride; ARQ-092 hydrochloride; Miransertib (ARQ 092)HCl; 3-{3-[4-(1-aminocyclobutyl)phenyl]-5-phenylimidazo[4,5-b]pyridin-2-yl}pyridin-2-amine hydrochloride
CAS No.:
1313883-00-9
Compound CID:
67305743
Formula:
C27H25ClN6
Formula Weight:
468.98
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Miransertib (ARQ 092) HCl is utilized in molecular pharmacology as a potent and selective allosteric AKT inhibitor to investigate the suppression of the PI3K/AKT signaling cascade in various malignant models.
Library Information
Target:
Akt
Receptor:
Akt
Pathways:
PI3K/Akt/mTOR signaling
Plate Number:
L6700-10
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
75 mg/mL; 159.92 mM
Ethanol Max Solubility:
4 mg/mL
ALogP:
4.98
HBA_Count:
3
HBD_Count:
2
Rotatable Bond:
4
