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Vacuolin-1
Cat. No.:
OB0225LY-0330
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Product Overview
Description:
Vacuolin-1 is a potent and selective PIKfyve inhibitor and inhibits late‐stage autophagy by impairing lysosomal maturation.
Synonym:
351986-85-1; 3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone; 4-(2-(3-Iodobenzylidene)hydrazinyl)-6-morpholino-N, N-diphenyl-1,3,5-triazin-2-amine; 2-N-[(E)-(3-Iodophenyl)methylideneamino]-6-morpholin-4-yl-4-N,4-N-diphenyl-1,3,5-triazine-2,4-diamine; 4-[(2E)-2-[(3-Iodophenyl)methylidene]hydrazin-1-yl]-6-(morpholin-4-yl)-N, N-diphenyl-1,3,5-triazin-2-amine
CAS No.:
351986-85-1
Compound CID:
9661141
Formula:
C26H24IN7O
Formula Weight:
577.42
Specification
Relative Density:
1.53 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Vacuolin-1 can be used in cell biology research or play an important role in the exploration of autophagy mechanism.
Library Information
Targets:
PI3K family
Receptors:
Autophagy; PIKfyve
Pathways:
PI3K/Akt/mTOR signaling; Autophagy
Plate Number:
AOCL-5
Plate Location:
c4
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
5.77 mg/mL; 10 mM
