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Lipid A4
Cat. No.:
OB0626WX-3866
Appearance:
Liquid
Purity:
≥95%
Identity:
Confirmed by NMR, TLC, and IR.
Size:
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Product Overview
Description:
Lipid A4 is a branched-chain ionizable cationic lipidoid designed with a precise hydrophobic tail topology that dictates unique tissue-tropism profiles for encapsulated expression transcripts. Unlike standard liver-directed lipidoids, this advanced framework directs cargo accumulation toward reproductive and extra-embryonic tissues while successfully traversing highly restrictive physiological barriers, such as the blood-brain barrier, to induce robust central nervous system reporter expression without triggering tissue toxicity.
Synonyms:
1,1'-((2-(2-(4-(2-((2-(2-(bis(2-hydroxydodecyl)amino)ethoxy)ethyl)(2-hydroxydodecyl)amino)ethyl)piperazin-1-yl)ethoxy)ethyl)azanediyl)bis(dodecan-2-ol); C12–4 C12-494 Lipid F3; C12-4 (Lipid A4); C12-4; 2639634-71-0
CAS No.:
2639634-71-0
Compound CID:
167248357
Formula:
C74H153N5O7
Formula Weight:
1225
Specification
Solubility in Ethanol:
10 mg/mL
Storage:
Storage at -20°C.
Applications:
Lipid A4 serves as a research lipid for constructing lipid nanoparticle formulations and evaluating delivery performance. It supports optimization of formulation parameters, comparative assessment of lipid structures, and investigation of lipid-mediated nucleic acid delivery.
