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KRAS inhibitor-9
Cat. No.:
OB0225WX-1896
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
KRAS inhibitor-9 is a potent KRAS antagonist (Kd: 92 μM) that blocks GTP-KRAS formation, leading to downstream signaling disruption and G2/M cell cycle arrest.
Synonym:
DUN09716; 300809-71-6; 4-(benzo[d]thiazol-2-ylthio)-3-chloroaniline; 4-(1,3-benzothiazol-2-ylsulfanyl)-3-chloroaniline; 4-(2-Benzothiazolylthio)-3-chlorobenzenamine; E75345; 4-(1,3-benzothiazol-2-ylthio)-3-chloroaniline
CAS No.:
300809-71-6
Compound CID:
667738
Formula:
C13H9ClN2S2
Formula Weight:
292.81
Specification
Relative Density:
1.49 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
KRAS inhibitor-9 is used in medicinal chemistry research as a small molecule inhibitor to explore the structural requirements for targeting KRAS-mediated protein-protein interactions.
Library Information
Target:
Kras
Receptor:
KRAS; Ras
Pathways:
MAPK
Plate Number:
AOCL-25
Plate Location:
c8
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
230 mg/mL; 785.49 mM
