HTR2C Blocking Peptide (C-QVENLELPVN)

Cat. No.: OB0526-WX66

Origin: Synthetic

Conjugation: Unconjugate

Species Reactivity: Human; Mouse; Rat; Dog; Cow

Size:

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Product Overview

Description: HTR2C Blocking Peptide (C-QVENLELPVN) is an antigen-matched synthetic peptide corresponding to a defined region of the HTR2C protein. Pre-incubation with compatible antibodies effectively blocks specific target recognition, facilitating validation of antibody-dependent staining and immunoblotting results. It is useful for antibody characterization and quality control applications.

Sequence: C-QVENLELPVN

Molecular Weight: 1241.4 Da

Purity: ≥95%

Applications: Western blotting; ELISA; IHC; IF; Functional Assay; Cell Culture; Binding Assay

Specification

Storage: Storage at -20°C.

Shipping Condition: Shipped with ice packs.

Handling Notes: During shipping, trace amounts of the blocking peptide may adhere to the interior surface of the vial cap. Before opening, it is highly recommended to briefly centrifuge the vial to bring all contents to the bottom.

Target Profile

Full Name: 5-hydroxytryptamine receptor 2C

Alternative Names: HTR2C; 5-HT-2C; 5-HT2C; 5-HTR2C; Serotonin receptor 2C; 5-HT1C; HTR1C

Summary: 5-Hydroxytryptamine receptor 2C (5-HT2C) is a seven-transmembrane G protein-coupled receptor activated by serotonin. Its signaling is influenced by RNA editing, which converts selected adenosine residues in the receptor mRNA to inosine and can alter the intracellular receptor domain and its ability to interact with G proteins. Variations in RNA editing, as well as genetic differences in regulatory and coding regions, have been investigated in relation to psychiatric and behavioral conditions. Multiple alternatively spliced transcript variants have also been reported.

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