HSD11B1 Blocking Peptide (CTSYNMDRFINK)

Cat. No.: OB0526-WX64

Origin: Synthetic

Conjugation: Unconjugate

Species Reactivity: Human; Cow

Size:

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Product Overview

Description: HSD11B1 Blocking Peptide (CTSYNMDRFINK) is a sequence-specific synthetic peptide corresponding to an antigenic region of the HSD11B1 protein. It is optimized for antibody blocking applications and assists researchers in verifying antibody selectivity and target-specific signal generation. The peptide is suitable for western blotting, immunohistochemistry, and immunofluorescence assays.

Sequence: CTSYNMDRFINK

Molecular Weight: 1507.7 Da

Purity: ≥95%

Applications: Western blotting; ELISA; IHC; IF; Functional Assay; Cell Culture; Binding Assay

Specification

Storage: Storage at -20°C.

Shipping Condition: Shipped with ice packs.

Handling Notes: During shipping, trace amounts of the blocking peptide may adhere to the interior surface of the vial cap. Before opening, it is highly recommended to briefly centrifuge the vial to bring all contents to the bottom.

Target Profile

Full Name: Hydroxysteroid 11-Beta Dehydrogenase 1

Alternative Names: HSD11B1; 11-Beta-HSD1; Prev. Symbol: HSD11; HSD11L; Prev. Symbol: HSD11B; 11-DH; SDR26C1; Short Chain Dehydrogenase/Reductase Family 26C, Member 1; Corticosteroid 11-Beta-Dehydrogenase Isozyme 1; Hydroxysteroid (11-Beta) Dehydrogenase 1; 11-Beta-Hydroxysteroid Dehydrogenase 1; CORTRD2; 7-Oxosteroid Reductase; HDL

Summary: HSD11B1 encodes an enzyme that primarily converts cortisone to the active glucocorticoid cortisol in humans. It is expressed in several metabolic tissues, including liver and adipose tissue, and regulates local glucocorticoid availability. HSD11B1 is studied for its involvement in glucocorticoid metabolism, adipose tissue function, and metabolic processes associated with obesity and insulin resistance.

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